The selective catalytic deoxygenation of oxy-organics in Fischer-Tropsch mixed oil for its high value utilization is challenging. Herein

a BaCO

3

/γ-Al

2

O

3

catalyst was prepared calcining γ-Al

2

O

3

with BaCO

3

and the acid-alkalinity of the catalyst was regulated by introducing alkaline Ba basic sties. In a continuous fixed-bed reactor with a feed mass space velocity of 1 h

-1

and reaction temperature of 330 ℃

BaCO

3

/γ-Al

2

O

3

catalyst can efficiently catalyzed the deoxygenation removal of 1-octanol in Fischer-Tropsch C10 mixture oil. It also inhibited the isomerization of 1-decene in the C10 mixture. The catalytic deoxygenation kinetics of 1-octanol were also studied. The reaction was endothermic with an activation energy of 64 kJ·mol

-1

and a reaction order of 2. In addition

theoretical studies revealed the adsorption and activation of 1-decene on the Lewis acidic site and the alkaline Ba basic sites

1-decene was more easily underwent isomerization into 2-decene at Lewis acid sites. This research provides a useful method to enable the industrial application of catalytic deoxygenation of alcohols in Fischer-Tropsch synthetic oil.