Efficient and convenient treatment of industrial dyeing wastewater is of great significance to guarantee human and animal health. This work presented the enhanced catalytic activity at pH 3.0 of laccase immobilized on amino-functionalized ZnFe

2

O

4

nanoparticles (ZnFe

2

O

4

-laccase) and its application for the degradation of textile dyes. Due to the existence of a large number of oxygen vacancies on the surface of the ZnFe

2

O

4

nanoparticles

negative ions accumulated on the magnetic carriers

which resulted in a harsh optimal pH value of the ZnFe

2

O

4

-laccase. Laccase activity assays revealed that the ZnFe

2

O

4

-laccase possessed superior pH and thermal stabilities

excellent reusability

and noticeable organic solvent tolerance. Meanwhile

the ZnFe

2

O

4

laccase presented efficient and sustainable degradation of high concentrations of textile dyes. The initial decoloration efficiencies of malachite green (MG)

brilliant green (BG)

azophloxine

crystal violet (CV)

reactive blue 19 (RB19)

and procion red MX-5B were approximately 99.1%

95.0%

93.3%

87.4%

86.1%

and 85.3%

respectively. After 10 consecutive reuses

the degradation rates of the textile dyes still maintained about 98.2%

92.5%

83.2%

81.5%

79.8% and 65.9%

respectively. The excellent dye degradation properties indicate that the ZnFe

2

O

4

-laccase has a technical application in high concentrations of dyestuff treatment.