Bio-inspired enantioseparation for chiral compounds

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第25届中国过程控制会议专栏 | Updated：2026-01-06

- Bio-inspired enantioseparation for chiral compounds
- Bio-inspired enantioseparation for chiral compounds
- 中国化学工程学报（英文版） 2016年24卷第1期页码：31-38
- Affiliations：
  
  2 School of Chemistry and Chemical Engineering, Shihezi University,Shihezi,China,832000
- Author bio：
- Funds：
- DOI：10.1016/j.cjche.2015.07.003
  中图分类号：
- 纸质出版：2016
- Accepted：
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Yan Fu, Jinjin Yang, Jinli Zhang, 等. Bio-inspired enantioseparation for chiral compounds[J]. 中国化学工程学报（英文版）, 2016,24(1):31-38.

Yan Fu, Jinjin Yang, Jinli Zhang, Wei Li. Bio-inspired enantioseparation for chiral compounds[J]. Chin.J.Chem.Eng., 2016, 24(1): 31-38.
Yan Fu, Jinjin Yang, Jinli Zhang, 等. Bio-inspired enantioseparation for chiral compounds[J]. 中国化学工程学报（英文版）, 2016,24(1):31-38. DOI： 10.1016/j.cjche.2015.07.003.

Yan Fu, Jinjin Yang, Jinli Zhang, Wei Li. Bio-inspired enantioseparation for chiral compounds[J]. Chin.J.Chem.Eng., 2016, 24(1): 31-38. DOI： 10.1016/j.cjche.2015.07.003.

Biomacromolecules including protein and nucleic acids are considered as promising chiral selectors in the fields of enantioselective separation

owing to their inherent chirality

polymorphous structures

stable physicochemical properties

good biocompatibility as well as susceptible modification and regulation. In this review

firstly

enantioselective recognition mechanismof proteins and nucleic acids toward different enantiomers is discussed

as well as their potential applications on the chiral separation of racemic compounds. Secondly

preparative enantioseparation adopting biomolecule-modified hybrid materials including porous microspheres

magnetic nanoparticles and affinity membranes

are introduced respectively. Finally

novel chiroptical materials constructed on the basis of chiral induction

transfer

amplification and transcription

are recognized as promising candidates in future applications.

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