Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510

Qin Luo; Hongbo Hu; Huasong Peng; Xuehong Zhang; Wei Wang

doi:10.1016/j.cjche.2015.01.001

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Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510

生物技术与生物工程 | Updated：2026-01-06

- Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510
- Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510
- 中国化学工程学报（英文版） 2015年23卷第4期页码：699-703
- Affiliations：
  
  State Key Laboratory of Microbial Metabolism, School of Life Science and Biotechnology, Shanghai Jiao Tong University,Shanghai,China,200240
- Author bio：
- Funds：
- DOI：10.1016/j.cjche.2015.01.001
  中图分类号：
- 纸质出版：2015
- Accepted：
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Qin Luo, Hongbo Hu, Huasong Peng, 等. Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510[J]. 中国化学工程学报（英文版）, 2015,23(4):699-703.

P510[J]. Chinese Journal of Chemical Engineering, 2015, 23(4): 699-703.
Qin Luo, Hongbo Hu, Huasong Peng, 等. Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510[J]. 中国化学工程学报（英文版）, 2015,23(4):699-703. DOI： 10.1016/j.cjche.2015.01.001.

P510[J]. Chinese Journal of Chemical Engineering, 2015, 23(4): 699-703. DOI： 10.1016/j.cjche.2015.01.001.

摘要

Abstract

Phenazine antibiotics phenazine-1-carboxylic acid (PCA) and 1-hydroxyphenazine (1-OH-PHZ) were purified from culture broth and mycelia of Streptomyces griseoluteus P510. Both PCA and 1-OH-PHZ exhibit strong antifun-gal activity against six plant pathogens

especially Fusarium oxysporium

with minimal inhibition concentrations less than 1 and 2 μg·ml

-1

for PCA and 1-OH-PHZ

respectively. The presence of PCA and 1-OH-PHZ indicates that S. griseoluteus P510 can be used as a potential source of pesticides.

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