陈国, 杨道茂, 肖雅琴, 等. Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process[J]. 中国化学工程学报(英文版), 2011,19(6):1023-1027.
CHEN Guo, YANG Daomao, XIAO Yaqin, CHEN Hongwen. Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process[J]. , 2011, 19(6): 1023-1027.
陈国, 杨道茂, 肖雅琴, 等. Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process[J]. 中国化学工程学报(英文版), 2011,19(6):1023-1027.DOI: 10.1016/S1004-9541(11)60086-4.
CHEN Guo, YANG Daomao, XIAO Yaqin, CHEN Hongwen. Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process[J]. , 2011, 19(6): 1023-1027.DOI: 10.1016/S1004-9541(11)60086-4.
Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process
3-Hydroxypropionaldehyde (3-HPA) is a potential valuable chemical and new broad-spectrum antimicrobial substance. In order to improve the conversion of 3-HPA/glycerol
our work studied the two-step process from glycerol to 3-HPA
and investigated the influence of cell harvest time
glycerol concentration
biomass con-centration
pH and temperature on the production of 3-HPA by
Lactobacillus reuteri
CG001
respectively. The results showed that molar conversion yield of 3-HPA/glycerol reached 97.9% under the condition that 200 mmol·L
-1
glycerol was converted by 25.3 g·L
-1
resting cell for 1 h at 30℃. The cells could not be reused directly because the
L. reuteri
almost lost its bioconversion activity completely
but the ability of glycerol conversion could gradually recover if the fresh medium was added to the deactivated cell for 4 h.
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相关作者
Han Zhang
Yunpeng Bai
Ning Zhu
Jianhe Xu
Chen Ma
Jing Wang
Xuelin Wang
Dandan Mai
相关机构
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology
College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University
State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University