Isolation and Purification of Triptolide from the Leaves of <i>Tripterygium wilfordii Hook F</i>

沈剑; 何潮洪

doi:10.1016/S1004-9541(09)60124-5

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Isolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F

Updated：2026-01-06

- Isolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F
- Isolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F
- 中国化学工程学报（英文版） 2010年18卷第5期页码：750-754
- Affiliations：
  
  State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang Uni versity,Hangzhou,China,310027
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (20576113);Zhejiang Provincial Natural Science Foundation of China (R4090358)
- DOI：10.1016/S1004-9541(09)60124-5
  中图分类号：
- 纸质出版：2010
- Accepted：
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沈剑, 何潮洪. Isolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F[J]. 中国化学工程学报（英文版）, 2010,18(5):750-754. DOI: 10.1016/S1004-9541(09)60124-5.

[J]. , 2010, 18(5): 750-754.
沈剑, 何潮洪. Isolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F[J]. 中国化学工程学报（英文版）, 2010,18(5):750-754. DOI: 10.1016/S1004-9541(09)60124-5. DOI：

[J]. , 2010, 18(5): 750-754. DOI： 10.1016/S1004-9541(09)60124-5.

摘要

Abstract

Triptolide is an important active component of

Tripterygium wilfordii Hook

F (TWHF) and possesses anti-inflammatory

immunosuppressive

male anti-fertility

and anticancer properties. A new method combining different techniques

including solid-liquid extraction

liquid-liquid partition

column chromatography and high-speed counter-current chromatography (HSCCC) but avoiding the use of chloroform

was developed for the isolation and purification of triptolide from the leaves of TWHF. 48 mg of triptolide at 96.5% purity was obtained from 1 kg of air-dried leaves of TWHF.

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Isolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F

Isolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F

DOI：10.1016/S1004-9541(09)60124-5

摘要

Abstract

关键词

Keywords

references