Graphene oxide (GO) channels exhibit unique mass transport behaviors due to their flexibility

controllable thinness and extraordinary physicochemical properties

enabling them to be widely used for adsorption and membrane separation. Nevertheless

the adsorption behavior of nanosized contaminants within the channels of GO membrane has not been fully discussed. In this study

we fabricated a GO membrane (PG

n

where

n

represents the deposition cycles of GO) with multi channels

via

the cross-linking of GO and multibranched poly(ethyleneimine) (PEI). Phenol was used as molecularprobe to determine the correlations between dynamic adsorption behavior and structural parameters of the multilevel GO/PEI membrane. PG8 shows higher adsorption capacities and affinity

which is predominantly attributed to the multichannel structure providing a large specific surface for phenol adsorption

enhancing the accessibility of active sites for phenol molecules and the transport of phenol. Density functional theory calculations demonstrate that the adsorption mechanism of phenol within GO channel is energetically oriented by hydrogen bonds

which is dominated by oxygen-containing groups compared to amino group

s. Particularly

the interfaces which facilitate strong π-π interaction and hydrogen bonds maybe the most active regions. Moreover

the as-prepared PG8 membrane showed outstanding performance for other contaminants such as methyl orange and Cr(VI). It is anticipated that this study will have implications for design of GO-related environmental materials with enhanced efficiency.