Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”

Renjie Xu; Min Zheng; Jiao Chen; Hongkun Zhao

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Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”

Chemical Engineering Thermodynamics | Updated：2026-01-06

- Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”
- Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”
- 中国化学工程学报（英文版） 2018年26卷第10期页码：2127-2129
- Affiliations：
  
  2 College of Chemistry & Chemical Engineering, Yangzhou University,Yangzhou,China,225002
- Author bio：
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  中图分类号：
- 纸质出版：2018
- Accepted：
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Renjie Xu, Min Zheng, Jiao Chen, 等. Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”[J]. 中国化学工程学报（英文版）, 2018,26(10):2127-2129.

Renjie Xu, Min Zheng, Jiao Chen, Hongkun Zhao. Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”[J]. Chin.J.Chem.Eng., 2018, 26(10): 2127-2129.
Renjie Xu, Min Zheng, Jiao Chen, 等. Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”[J]. 中国化学工程学报（英文版）, 2018,26(10):2127-2129. DOI：

Renjie Xu, Min Zheng, Jiao Chen, Hongkun Zhao. Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”[J]. Chin.J.Chem.Eng., 2018, 26(10): 2127-2129. DOI：

摘要

Abstract

Problem was discussed on the reported equation parameters by Zhou and co-workers[Chinese Journal of Chemical Engineering 25 (10) (2017) 1461-1466] for expressing the meropenem trihydrate solubility in binary (water + acetone and water + tetrahydrofuran) mixtures with the modified Apelblat equation. The reported model parameters do not back-calculate correctly the evaluated solubility as shown in their published work. The reported parameters of the modified Apelblat equation tabulated in Tables 3 and 4 by Zhou and coworkers are in mistake.

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