A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility

Noel Jacob Kaleekkal; A. Thanigaivelan; M. Tarun; D. Mohan

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A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility

材料与产品工程 | Updated：2026-01-06

- A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility
- A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility
- 中国化学工程学报（英文版） 2015年23卷第7期页码：1236-1244
- Affiliations：
  
  Membrane Laboratory, Department of Chemical Engineering, Anna University,Chennai,India
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：2015
- Accepted：
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Noel Jacob Kaleekkal, A. Thanigaivelan, M. Tarun, 等. A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility[J]. 中国化学工程学报（英文版）, 2015,23(7):1236-1244.

Noel Jacob Kaleekkal, A. Thanigaivelan, M. Tarun, D. Mohan. A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility[J]. Chin.J.Chem.Eng., 2015, 23(7): 1236-1244.
Noel Jacob Kaleekkal, A. Thanigaivelan, M. Tarun, 等. A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility[J]. 中国化学工程学报（英文版）, 2015,23(7):1236-1244. DOI：

Noel Jacob Kaleekkal, A. Thanigaivelan, M. Tarun, D. Mohan. A functional PES membrane for hemodialysis—Preparation, characterization and biocompatibility[J]. Chin.J.Chem.Eng., 2015, 23(7): 1236-1244. DOI：

摘要

Abstract

In this work

we evaluate the properties of solution casted polysulfone (PSf)/sulfonated polyethersulfone (SPES) blend membranes prepared by non-solvent induced phase inversion technique. The morphologies of these blend membranes

observed using scanning electron microscopy (SEM) and atomic force microscopy (AFM) imaging

indicated a smoother skin layer and an increased number of highly interconnected pores in the sub layer. The efficacy of the prepared membranes was evaluated in terms of porosity

ultrafiltration rate (UFR)

molecular weight cut-off (MWCO) and mean pore size. The hydrophilicity of these membranes was in consonance with contact angle values. It was observed that the selectivity and the UFR of the blend membranes were higher when compared to pristine membranes. Furthermore

these blend membranes demonstrated an increase in biocompatibility—prolonged blood clotting time

suppressed platelet adhesion

reduced protein adsorption and lower complement activation. These membranes were also investigated for uremic solute removal. Diffusive permeability of middle molecular weight cytochrome-c revealed an increase from 8 × 10

-4

cm·s

-1

to 18 × 10

-4

cm·s

-1

and illustrates the possibility that these s

ulfonated PES/PSf blend membranes can be used to prepare membrane modules for hemodialysis applications.

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