Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510
摘要
Abstract
Phenazine antibiotics phenazine-1-carboxylic acid (PCA) and 1-hydroxyphenazine (1-OH-PHZ) were purified from culture broth and mycelia of Streptomyces griseoluteus P510. Both PCA and 1-OH-PHZ exhibit strong antifun-gal activity against six plant pathogens
especially Fusarium oxysporium
with minimal inhibition concentrations less than 1 and 2 μg·ml
-1
for PCA and 1-OH-PHZ
respectively. The presence of PCA and 1-OH-PHZ indicates that S. griseoluteus P510 can be used as a potential source of pesticides.
关键词
Keywords
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