Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process

陈国; 杨道茂; 肖雅琴; 陈宏文

doi:10.1016/S1004-9541(11)60086-4

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Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process

Updated：2026-01-06

- Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process
- Chinese Journal of Chemical Engineering Vol. 19, Issue 6, Pages: 1023-1027(2011)
- Affiliations：
  
  Department of Bioengineering and Biotechnology, Huaqiao University,Xiamen,China,361021
- Author bio：
- Funds：
- DOI：10.1016/S1004-9541(11)60086-4
  CLC：
- Published：2011
- Accepted：
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CHEN Guo, YANG Daomao, XIAO Yaqin, CHEN Hongwen. Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process[J]. , 2011, 19(6): 1023-1027.
DOI：

CHEN Guo, YANG Daomao, XIAO Yaqin, CHEN Hongwen. Influence of Conditions on Reuterin Accumulation by the Resting Cell Biotransformation Process[J]. , 2011, 19(6): 1023-1027. DOI： 10.1016/S1004-9541(11)60086-4.

摘要

Abstract

3-Hydroxypropionaldehyde (3-HPA) is a potential valuable chemical and new broad-spectrum antimicrobial substance. In order to improve the conversion of 3-HPA/glycerol

our work studied the two-step process from glycerol to 3-HPA

and investigated the influence of cell harvest time

glycerol concentration

biomass con-centration

pH and temperature on the production of 3-HPA by

Lactobacillus reuteri

CG001

respectively. The results showed that molar conversion yield of 3-HPA/glycerol reached 97.9% under the condition that 200 mmol·L

-1

glycerol was converted by 25.3 g·L

-1

resting cell for 1 h at 30℃. The cells could not be reused directly because the

L. reuteri

almost lost its bioconversion activity completely

but the ability of glycerol conversion could gradually recover if the fresh medium was added to the deactivated cell for 4 h.

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