Diffusion Coefficients of L-Arginine in Non-Newtonian Fluid

朱春英; 马友光; 季喜燕

doi:10.1016/S1004-9541(09)60005-7

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Diffusion Coefficients of L-Arginine in Non-Newtonian Fluid

Updated：2026-01-06

- Diffusion Coefficients of L-Arginine in Non-Newtonian Fluid
- Chinese Journal of Chemical Engineering Vol. 16, Issue 6, Pages: 856-860(2008)
- Affiliations：
  
  School of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, Tianjin University,Tianjin,China,300072
- Author bio：
- Funds：
- DOI：10.1016/S1004-9541(09)60005-7
  CLC：
- Published：2008
- Accepted：
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ZHU Chunying, MA Youguang, JI Xiyan. Diffusion Coefficients of L-Arginine in Non-Newtonian Fluid[J]. , 2008, 16(6): 856-860.
DOI：

ZHU Chunying, MA Youguang, JI Xiyan. Diffusion Coefficients of L-Arginine in Non-Newtonian Fluid[J]. , 2008, 16(6): 856-860. DOI： 10.1016/S1004-9541(09)60005-7.

摘要

Abstract

L-Arginine is an important component of amino acid injection.Its diffusion in body fluid and blood is of key importance to understand drug diffusion and drug release.As a fundamental demand for study and being a considerably valuable reference for application

in this study

the diffusion coefficients of L-arginine in polyacrylamide(PAM) aqueous solution used as non-Newtonian fluid similar to blood and body fluid were measured using a holographic interferometer.The effects of interaction among molecules and solution concentration on diffusion were analyzed and discussed

respectively.Based on the obstruction-scaling model

a novel modified model was presented for predicting diffusivity of solute in non-Newtonian fluid.Good agreement was achieved between the calculated value and the experimental data.

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