This article is a preliminary study on antibacterial blends of polycaprolactone

chitosan and quaternized chitosan by melt processing. Blends were characterized

mechanical test and antibacterial evaluation against

Escherichia coli

and

Staphylococcus aureus

were conducted. Results showed that the antibacterial potential of chitosan was limited in blends and polycaprolactone/chitosan did not show significant antibacterial effect compared with neat polycaprolactone (PCL). Inhibition rates of polycaprolactone/quaternized chitosan were 39.2%-99.9% against

Escherichia coli

while inhibition rate was 40.9%-99.9% against

Staphylococcus aureus

. When quaternized chitosan (QCTS) content was up to 20%

blends exhibited 99.9% inhibition rates against both two types of bacteria.