Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”
Chemical Engineering Thermodynamics|Updated:2026-01-06
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Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”
Chinese Journal of Chemical EngineeringVol. 26, Issue 10, Pages: 2127-2129(2018)
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2 College of Chemistry & Chemical Engineering, Yangzhou University,Yangzhou,China,225002
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Published:2018
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Renjie Xu, Min Zheng, Jiao Chen, Hongkun Zhao. Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”[J]. Chin.J.Chem.Eng., 2018, 26(10): 2127-2129.
DOI:
Renjie Xu, Min Zheng, Jiao Chen, Hongkun Zhao. Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”[J]. Chin.J.Chem.Eng., 2018, 26(10): 2127-2129.DOI:
Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary (water + acetone/tetrahydrofuran) solvent mixtures”
Problem was discussed on the reported equation parameters by Zhou and co-workers[Chinese Journal of Chemical Engineering 25 (10) (2017) 1461-1466] for expressing the meropenem trihydrate solubility in binary (water + acetone and water + tetrahydrofuran) mixtures with the modified Apelblat equation. The reported model parameters do not back-calculate correctly the evaluated solubility as shown in their published work. The reported parameters of the modified Apelblat equation tabulated in Tables 3 and 4 by Zhou and coworkers are in mistake.
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