A novel purification process for dodecanedioic acid by molecular distillation

doi:10.1016/j.cjche.2014.10.019

Abstract

Abstract: A novel purification process is involved to obtain the high purity [>99%(by mass)] dodecanedioic acid (DC₁₂). It involves a re-crystallization followed bymolecular distillation fromthe crude product. The objective of this study is to investigate general conditions, feed rate, distilling temperature and vacuum, necessary for centrifugal distillation of DC₁₂. Under the optimum conditions, distilling temperature 180℃, pressure 30 Pa and feed flow rate 700 ml·h^-1, the purity of DC₁₂ in the residence reached 97.55% with a yield of 53.18% by the analysis of gas chromatography. Multiple-pass distillation made a considerable contribution by improving the purity to 99.22%. Additionally, the effect of pretreatment (re-crystallization) on distillation process was revealed through a series of comparative experiments.

Key words: Dodecanedioic acid, Fermentation, Purification, Separation, Molecular distillation

摘要： A novel purification process is involved to obtain the high purity [>99%(by mass)] dodecanedioic acid (DC₁₂). It involves a re-crystallization followed bymolecular distillation fromthe crude product. The objective of this study is to investigate general conditions, feed rate, distilling temperature and vacuum, necessary for centrifugal distillation of DC₁₂. Under the optimum conditions, distilling temperature 180℃, pressure 30 Pa and feed flow rate 700 ml·h^-1, the purity of DC₁₂ in the residence reached 97.55% with a yield of 53.18% by the analysis of gas chromatography. Multiple-pass distillation made a considerable contribution by improving the purity to 99.22%. Additionally, the effect of pretreatment (re-crystallization) on distillation process was revealed through a series of comparative experiments.

关键词: Dodecanedioic acid, Fermentation, Purification, Separation, Molecular distillation

Jiang Yu, Xigang Yuan, Aiwu Zeng. A novel purification process for dodecanedioic acid by molecular distillation[J]. , 2015, 23(3): 499-504.

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