SCI和EI收录∣中国化工学会会刊

中国化学工程学报 ›› 2019, Vol. 27 ›› Issue (3): 660-667.doi: 10.1016/j.cjche.2018.05.008

• Energy, Resources and Environmental Technology • 上一篇    下一篇

An ultrasonic-ionic liquid process for the efficient acid catalyzed hydrolysis of feather keratin

Song Ding1, Yang Sun1, Hongyue Chen2, Chao Xu2, Yi Hu1,2,3   

  1. 1 School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China;
    2 School of Biotechnology and Pharmaceutical Engineering of Nanjing Tech University, Nanjing 211816, China;
    3 School of Pharmaceutical Sciences, State Key Laboratory of Material-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211816, China
  • 收稿日期:2018-02-01 修回日期:2018-05-06 出版日期:2019-03-28 发布日期:2019-04-25
  • 通讯作者: Yi Hu,E-mail address:huyi@njtech.edu.cn E-mail:huyi@njtech.edu.cn
  • 基金资助:

    Supported by the National Natural Science Foundation of China (21676143),the Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture,Self-Owned Research Project from Key Laboratory of Material-Oriented Chemical Engineering (ZK201603),Qing Lan Project of Jiang Su Province.

An ultrasonic-ionic liquid process for the efficient acid catalyzed hydrolysis of feather keratin

Song Ding1, Yang Sun1, Hongyue Chen2, Chao Xu2, Yi Hu1,2,3   

  1. 1 School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China;
    2 School of Biotechnology and Pharmaceutical Engineering of Nanjing Tech University, Nanjing 211816, China;
    3 School of Pharmaceutical Sciences, State Key Laboratory of Material-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211816, China
  • Received:2018-02-01 Revised:2018-05-06 Online:2019-03-28 Published:2019-04-25
  • Contact: Yi Hu,E-mail address:huyi@njtech.edu.cn E-mail:huyi@njtech.edu.cn
  • Supported by:

    Supported by the National Natural Science Foundation of China (21676143),the Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture,Self-Owned Research Project from Key Laboratory of Material-Oriented Chemical Engineering (ZK201603),Qing Lan Project of Jiang Su Province.

摘要: A novel efficient method for hydrolyzing feather keratin using an ultrasonic-ionic liquid coupling process has been developed, with reaction conditions optimized using response surface analysis of data obtained from single factor optimization studies. Ultrasonic irradiation (225 W power) of feathers in 8.4 mol·L-1 hydrochloric acid containing 1-butyl-3-methylimidazolium chloride as a cosolvent at 80℃ for 1.4 h, followed by heating at 110℃ for 8.3 h, resulted in hydrolysis of their keratin component in an excellent 83.1% yield. Compared with previous methods, this new method employs reduced amounts of hydrochloric acid, shorter reaction time, and affords amino acid hydrolysis products in higher yield.

关键词: Ionic liquid, Ultrasonic, Keratin, Hydrolysis, Amino acid

Abstract: A novel efficient method for hydrolyzing feather keratin using an ultrasonic-ionic liquid coupling process has been developed, with reaction conditions optimized using response surface analysis of data obtained from single factor optimization studies. Ultrasonic irradiation (225 W power) of feathers in 8.4 mol·L-1 hydrochloric acid containing 1-butyl-3-methylimidazolium chloride as a cosolvent at 80℃ for 1.4 h, followed by heating at 110℃ for 8.3 h, resulted in hydrolysis of their keratin component in an excellent 83.1% yield. Compared with previous methods, this new method employs reduced amounts of hydrochloric acid, shorter reaction time, and affords amino acid hydrolysis products in higher yield.

Key words: Ionic liquid, Ultrasonic, Keratin, Hydrolysis, Amino acid